Patients with moderate COVID-19 fared better in a recent study of 112, 269 patients when they were given aspirin on day one.
The study, Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19, was published Thursday by the Journal of American Medical Association (JAMA).
Dr. Jonathan Chow, the study’s lead author, is a medical researcher in George Washington University’s Department of Anesthesiology and Critical Care Medicine.
According to the group’s research, fewer deaths and pulmonary embolisms were recorded in patients who were given a five-day regimen of aspiring beginning on their first day of treatment.
Chow, et al, did note some differences in results based on age and other health conditions.
“Patients older than 60 years had significantly lower odds of in-hospital mortality, whereas those who were younger did not,” Chow explained, “Given prior studies that have shown increased mortality with age, it is not surprising that aspirin’s efficacy may be greater in older patients”
“Patients without comorbidities receiving early aspirin did not have lower odds of mortality,” he explained, adding “while those with at least one comorbidity had lower odds of mortality.”
It would seem, the older and/or sicker a patient was, the more they were helped by having early doses of aspirin added to their treatment.
The study was funded by the National Science Foundation, the National Institutes of Health and George Washington University, according to “The Epoch Times”. It was published in the Journal of the American Medical Association following peer review.
Dr. Chow said their findings were consistent with earlier studies of aspirin benefits. The doctor noted a pilot study, the Collaborative Registry to Understand the Sequelae of Harm in COVID-19 (CRUSH-COVID), determined combined prehospital and in-hospital aspirin use within the first 24 hours of admission was associated with decreased in-hospital mortality.
He next cited a study of 12 600 veterans that found lower odds of 30-day all-cause mortality in those who received aspirin as an outpatient.
The study noted two other related studies that did not provide conclusive evidence of aspirin treatments.
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